Paris, 9 January 2014

How fiber prevents diabetes and obesity

Scientists have known for the past twenty years that a fiber-rich diet protects the organism against obesity and diabetes but the mechanisms involved have so far eluded them. A French-Swedish team including researchers from CNRS, Inserm and the Université Claude Bernard Lyon 1 (Unité Inserm 855 “Nutrition et Cerveau”) has succeeded in elucidating this mechanism, which involves the intestinal flora and the ability of the intestine to produce glucose between meals. These results, published in the journal Cell on 9 January 2014, also clarify the role of the intestine and its associated microorganisms in maintaining glycaemia. They will give rise to new dietary recommendations to prevent diabetes and obesity.

To download the press release : Fibres


Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits
Filipe De Vadder, Petia Kovatcheva-Datchary, Daisy Goncalves, Jennifer Vinera, Carine Zitoun, Adeline Duchampt, Fredrik Bäckhed, Gilles Mithieux
Cell 9 January 2014


CNRS researcher l Gilles Mithieux l T +33 4 78 77 87 88 /
+33 6 07 39 71 92 l
CNRS press officer l Muriel Ilous l T +33 1 44 96 43 09 l


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